DG Preventive Essential
Allows us to know the risk of developing different actionable hereditary diseases.
Preventive test for actionable diseases
DG Preventive Essential is a test that analyzes the 81 actionable genes that are recommended for study by the ACMG (American College of Medical Genetics and Genomics) andthat are related to 37 high-incidence diseases, most of them cardiovascular diseases and cancer.
Its realization provides the following advantages:
- It reduces uncertainty and anxiety about the risk of having an actionable hereditary disease.
- It provides valuable information for the entire family, even for members who have not been tested.
- It allows for appropriate follow-up for each family member based on the results obtained.
- EDTA blood (1x 5 ml)
- Saliva (specific Isohelix kit)
- Buccal exudate (2x sterile isopes)
- Isolated DNA (>30 ng/μl in >100 μl)
Remember to label each sample with the patient's first and last name or with the identifier used on the request form.
Diseases studied
Hereditary heart disease
Cardiovascular diseases are the leading cause of death worldwide and up to 25% of sudden cardiac deaths are due to genetic abnormalities in genes responsible for the structure of the heart muscle or heart rhythm.
Hereditary cancer
Cancer is the second leading cause of death in the world and it is known that in up to 15% of cases there is a hereditary component.
Metabolic diseases
DG Preventive Essential includes the study of 11 additional actionable diseases, such as hereditary hemochromatosis, Fabry disease and Pompe disease.
Who is our DG Preventive Essential study aimed at?
- People with a family history of hereditary cardiovascular disease.
- People with a family history of hereditary cancer.
- Healthy people who are concerned about their own health care and that of their family members.
- Anyone who wants to know the risk of transmitting a genetic disease to their children.
We offer the possibility of performing the genetic study from a saliva sample. For this purpose, we provide our clients with saliva collection kits, so that the patient can collect the sample comfortably at home. Each kit contains a saliva collector, collection instructions, a request form and an informed consent form.
Technical characteristics
- Whole Exome Sequencing
- SureSelect Human All Exon V8 Library
- Illumina® technology NovaSeq 6000 platform
- Average coverage 100 x - 150 x
- Bioinformatics analysis using our software Genome One
- Classification of variants according to ACMG criteria
- Analysis of SNVs, Indels and CNVs
- Samples: EDTA blood, saliva and buccal exudate.
- Delivery time: 35-45 days
Other options available
DG Preventive Cardio
DG Preventive Cardio is a preventive genetic test that analyzes 124 actionable genes associated with the risk of developing 34 inherited cardiovascular diseases.
DG Preventive Cancer
DG Preventive Cancer is a preventive genetic test that studies 86 actionable genes related to different types of hereditary cancer.
DG Preventive Premium
DG Preventive Premium is a preventive genetic test that analyzes 344 genes related to the risk of developing hereditary cardiovascular diseases, hereditary cancer and autosomal recessive or X-linked diseases.
Our DG Preventive report
- All DG Preventive reports are written in a simple way so that they can be easily understood by the patient.
- Pathogenic and Probably Pathogenic variants are reported according to the ACMG classification.
- The possible outcomes and the implication of each of them are explained in detail.
- Recommendations for the patient and family members are included.
- Information on the genes analyzed and the diseases studied is included.
DG Preventive Essential
Allows us to know the risk of developing different actionable hereditary diseases.
Preventive test for actionable diseases
DG Preventive Essential is a test that analyzes the 81 actionable genes recommended for study by the ACMG(American College of Medical Genetics and Genomics) that are related to 37 high-incidence diseases, most of them cardiovascular diseases and cancer.
Its realization provides the following advantages:
- It reduces uncertainty and anxiety about the risk of having an actionable hereditary disease.
- It provides valuable information for the entire family, even for members who have not been tested.
- It allows for appropriate follow-up for each family member based on the results obtained.
Diseases studied
Hereditary karyopathies
Cardiovascular diseases are the leading cause of death worldwide and up to 25% of sudden cardiac deaths are due to genetic abnormalities in genes responsible for the structure of the heart muscle or heart rhythm.
Hereditary cancer
Cancer is the second leading cause of death in the world and it is known that in up to 15% of cases there is a hereditary component.
Metabolic diseases
DG Preventive Essential includes the study of 11 additional actionable diseases, such as hereditary hemochromatosis, Fabry disease and Pompe disease.
Who is our DG Preventive Essential study aimed at?
- People with a family history of hereditary cardiovascular disease.
- People with a family history of hereditary cancer.
- Healthy people who are concerned about their own health care and that of their family members.
- Anyone who wants to know the risk of transmitting a genetic disease to their children.
We provide our customers with saliva collection kits, so that the patient can collect the sample with total comfort at home.
Features
- Whole Exome Sequencing
- SureSelect Human All Exon V8 Library
- Illumina® technology NovaSeq 6000 platform
- Medium coverage 100-150x
- Bioinformatics analysis using our software Genome One
- Classification of variants according to ACMG criteria
- Analysis of SNVs, Indels and CNVs
- Samples: EDTA blood, saliva and buccal exudate.
- Delivery time: 35-45 days
Other options available
DG Preventive Cardio
DG Preventive Cardio is a preventive genetic test that analyzes 124 actionable genes associated with the risk of developing 34 inherited cardiovascular diseases.
DG Preventive Cancer
DG Preventive Cancer is a preventive genetic test that studies 86 actionable genes related to different types of hereditary cancer.
DG Preventive Premium
DG Preventive Premium is a preventive genetic test that analyzes 344 genes related to the risk of developing hereditary cardiovascular diseases, hereditary cancer and autosomal recessive or X-linked diseases.
Our DG Preventive genetic report
- All DG Preventive reports are written in a simple way so that they can be easily understood by the patient.
- Pathogenic and Probably Pathogenic variants are reported according to the ACMG classification.
- The possible outcomes and the implication of each of them are explained in detail.
- Recommendations for the patient and family members are included.
- Information on the genes analyzed and the diseases studied is included.
DG Preventive Essential
Allows us to know the risk of developing different actionable hereditary diseases.
Preventive test for actionable diseases
DG Preventive Essential is a test that analyzes the 81 actionable genes recommended for study by the ACMG(American College of Medical Genetics and Genomics) that are related to 37 high-incidence diseases, most of them cardiovascular diseases and cancer.
Its realization provides the following advantages:
- It reduces uncertainty and anxiety about the risk of having an actionable hereditary disease.
- It provides valuable information for the entire family, even for members who have not been tested.
- It allows for appropriate follow-up for each family member based on the results obtained.
Features
- Whole Exome Sequencing
- SureSelect Human All Exon V8 Library
- Illumina® technology NovaSeq 6000 platform
- Medium coverage 100-150x
- Bioinformatics analysis using our software Genome One
- Classification of variants according to ACMG criteria
- Analysis of SNVs, Indels and CNVs
- Samples: EDTA blood, saliva and buccal exudate.
- Delivery time: 35-45 days
DG Preventive Report
- All DG Preventive reports are written in a simple way so that they can be easily understood by the patient.
- Pathogenic and Probably Pathogenic variants are reported according to the ACMG classification.
- The possible outcomes and the implication of each of them are explained in detail.
- Recommendations for the patient and family members are included.
- Information on the genes analyzed and the diseases studied is included.