Protein validation

Protein validation

Clinical validation of proteins consists of using analysers for clinical use to quantify in biological samples proteins that have been found to be differentially expressed in basic research studies carried out using proteomic techniques and that are therefore considered as potential biomarkers of disease.

 

The list of proteins available for clinical validation is detailed below, together with information regarding the type of sample where they can be analysed and the volume required:

Clinical validation of proteins consists of using analysers for clinical use to quantify in biological samples proteins that have been found to be differentially expressed in basic research studies carried out using proteomic techniques and that are therefore considered as potential biomarkers of disease.

 

The list of proteins available for clinical validation is detailed below:

Alpha-1 Antitrypsin, Alpha-1 Acid Glycoprotein, Antithrombin III, Apolipoprotein A-I, Apolipoprotein A-II, Apolipoprotein B, Apolipoprotein C-II, Apolipoprotein C-III, Apolipoprotein E, Beta-2 Microglobulin, Ceruloplasmin, Cystatin C, C3 Complement, C4 Complement, Rheumatoid factor, Ferritin, Haptoglobin, Immunoglobulin A, Immunoglobulin E, Immunoglobulin G, Immunoglobulin M, Lipoprotein (a), Microalbumin, Prealbumin, C-reactive protein*, C-reactive protein ultra** and Transferrin.

*Dynamic range: 1-150 mg/L.

**Dynamic range: 0,05-10 mg/L. 

Protein Sample 1st protein (µL) 2nd protein (µL)
Alpha-1 Antitrypsin
Serum/plasma
80
20
Alpha-1 acid glycoprotein
Serum/plasma
80
20
Antithrombin III
Serum/plasma
80
20
Apolipoprotein A-I
Serum/plasma
80
20
Apolipoprotein A-II
Serum/plasma
80
20
Apolipoprotein B
Serum/plasma
80
20
Apolipoprotein C-II
Serum/plasma
80
20
Apolipoprotein C-III
Serum/plasma
80
20
Apolipoprotein E
Serum/plasma
80
20
Beta-2 Microglobulin
Serum/plasma/urine
80
20
Ceruloplasmin
Serum/plasma
80
20
Cystatin C
Serum/plasma
80
20
Complement C3
Serum/plasma
80
20
Complement C4
Serum/plasma
80
20
Rheumatoid factor
Serum/plasma
80
20
Ferritin
Serum/plasma
80
20
Haptoglobin
Serum/plasma
80
20
Immunoglobulin A
Serum/plasma
80
20
Immunoglobulin E
Serum/plasma
80
20
Immunoglobulin G
Serum/plasma
80
20
Immunoglobulin M
Serum/plasma
80
20
Lipoprotein (a)
Serum/plasma
80
20
Microalbumin
Urine
80
20
Prealbumin
Serum/plasma
80
20
C-reactive protein*
Serum/plasma
80
20
Ultra C-reactive protein**
Serum/plasma
80
20
Transferrin
Serum/plasma
80
20

*Dynamic range: 1-150 mg/L. **Dynamic range: 0,05-10 mg/L. 

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