Dreamgenics

Non-coding RNAs (ncRNAs) are RNA molecules without protein translation potential, but capable of modulating gene expression through different mechanisms. The ncRNA-mediated gene silencing constitutes an important type of epigenetic alterations and has been implicated in several human carcinogenesis. A growing number of studies have uncovered ... Read More

Since the 1990s, genetic testing in cardiology has been recommended for patients who have symptoms of inherited cardiovascular disease or are at high risk because there is a known pathogenic variant in their family. In 2020, the American Heart Association (AHA) issued a statement recommending genetic testing for patients diagnosed with an inherited cardiovascular ... Read More

Rheumatoid arthritis (RA) is a multifactorial, inflammatory and progressive autoimmune disease, most commonly found in people between the ages of 45 and 55, which mainly affects the joints, although it can also affect other parts of the body. It begins with a destruction of the synovial membrane that covers the joints, causing a picture of pain, swelling and ... Read More

The development of omics technologies in recent years has led to an increasing understanding of the pathophysiology of diseases and the discovery of potential biomarkers that can improve the diagnosis, prognosis and monitoring of how a disease responds to different treatments. This increase in the number of possible variables involved in the onset of disease is ... Read More

The so-called extracellular or circulating RNAs are RNA molecules that have been secreted outside the cells in which they have been transcribed and circulate in biological fluids. Although they were first described in the first half of the 20th century, it was not until the identification of microRNAs (miRNAs) in the first half of the ... Read more