Genomic analysis
Relevant clinical information
Deciphering DNA information
The analysis of massive sequencing data is a complex process that requires a high level of bioinformatics knowledge and large processing and storage resources.
At Dreamgenics we have own software and pipelines for the analysis of NGS data from the sequencing of genomes, exomes, trio exomes and targeted exomes.
Our bioinformatics analysis includes:
- Quality control of the sequences.
- Alignment of reads originated against reference genome.
- Detection of high quality variants (SNVs, translocations and CNVs).
- Filtering of common variants in the population.
- Annotation of variants obtained with multiple databases and prediction algorithms.
- Comparison between samples and extraction of recurrent variants.
We can perform bioinformatics analysis from different files depending on the sequencing technology used:
- Illumina®: FASTQ, BAM and VCF
- MGI: FASTQ, BAM and VCF
- Ion Torrent: VCF
You can send us your raw files on a hard disk or share them via FTP. If you have any questions please contact us by sending an email to info@dreamgenics.com or calling 985 088 180 and we will help you.
Results in Genome One Reports
We deliver the results of our genomic analysis through our Genome One Reports platform. A simple and intuitive web platform that will provide you with the following advantages:
- You will have access to the quality analysis of the sequences obtained.
- You will be able to configure customizable variant filters
- You will have the possibility to perform a pre-sorting of variants according to pathogenicity criteria chosen by you.
- You will be able to create your own databases generated by variant review or recurrence analysis.
- You will have the option to generate customized reports
We offer a wide variety of possibilities
Depending on the starting sample and the analysis to be performed, different libraries can be used. Contact us and we will help you to choose the best option for your project.
Genome
- Illumina® NovaSeq 6000 Platform
- Illumina® TruSeq DNA Nano Library
- Mean coverage >30x
- >1 μg of genomic DNA or >100ng of FFPE
- 75-180 Gb/sample
- Analysis of SNVs, indels and CNVs*.
- Results in Genome One Reports
Exome
- Illumina® NovaSeq 6000 Platform
- SureSelect Human All Exon V6/V8 Library
- Mean coverage >100x
- >1 μg of genomic DNA or >200ng FFPE
- 9-36 Gb/sample
- Analysis of SNVs, indels and CNVs*.
- Results in Genome One Reports
*CNVs whenever the experimental design permits.
Genomic analysis
Relevant clinical information
Deciphering DNA information
At Dreamgenics we have own software and pipelines for the analysis of NGS data from the sequencing of genomes, exomes, trio exomes and targeted exomes.
Our bioinformatics analysis includes:
- Quality control of the sequences.
- Alignment of reads originated against reference genome.
- Detection of high quality variants (SNVs, translocations and CNVs).
- Filtering of common variants in the population.
- Annotation of variants obtained with multiple databases and prediction algorithms.
- Comparison between samples and extraction of recurrent variants.
Results in Genome One Reports
We deliver the results of our genomic analysis through our Genome One Reports platform. A simple and intuitive web platform that will provide you with the following advantages:
- You will have access to the quality analysis of the sequences obtained.
- You will be able to configure customizable variant filters
- You will have the possibility to perform a pre-sorting of variants according to pathogenicity criteria chosen by you.
- You will be able to create your own databases generated by variant review or recurrence analysis.
- You will have the option to generate customized reports
We offer a wide variety of possibilities
Depending on the starting sample and the analysis to be performed, different libraries can be used. Contact us and we will help you to choose the best option for your project.
Genome
- Illumina® NovaSeq 6000 Platform
- Illumina® TruSeq DNA Nano Library
- Mean coverage >30x
- >1 μg of genomic DNA or >100ng of FFPE
- 75-180 Gb/sample
- Analysis of SNVs, indels and CNVs*.
- Results in Genome One Reports
Exome
- Illumina® NovaSeq 6000 Platform
- SureSelect Human All Exon V6/V8 Library
- Mean coverage >100x
- >1 μg of genomic DNA or >200ng FFPE
- 9-36 Gb/sample
- Analysis of SNVs, indels and CNVs*.
- Results in Genome One Reports
*CNVs whenever the experimental design permits.
Genomic analysis
Relevant clinical information
Deciphering DNA information
At Dreamgenics we have own software and pipelines for the analysis of NGS data from the sequencing of genomes, exomes, trio exomes and targeted exomes.
Our bioinformatics analysis includes:
- Quality control of the sequences.
- Alignment of reads originated against reference genome.
- Detection of high quality variants (SNVs, translocations and CNVs).
- Filtering of common variants in the population.
- Annotation of variants obtained with multiple databases and prediction algorithms.
- Comparison between samples and extraction of recurrent variants.
Results in Genome One Reports
- You will have access to the quality analysis of the sequences obtained.
- You will be able to configure customizable variant filters
- You will have the possibility to perform a pre-sorting of variants according to pathogenicity criteria chosen by you.
- You will be able to create your own databases generated by variant review or recurrence analysis.
- You will have the option to generate customized reports
We offer a wide variety of possibilities
Depending on the starting sample and the analysis to be performed, different libraries can be used. Contact us and we will help you to choose the best option for your project.
Genome
- Illumina® NovaSeq 6000 Platform
- Illumina® TruSeq DNA Nano Library
- Mean coverage >30x
- >1 μg of genomic DNA or >100ng of FFPE
- 75-180 Gb/sample
- Analysis of SNVs, indels and CNVs*.
- Results in Genome One Reports
Exome
- Illumina® NovaSeq 6000 Platform
- SureSelect Human All Exon V6/V8 Library
- Mean coverage >100x
- >1 μg of genomic DNA or >200ng FFPE
- 9-36 Gb/sample
- Analysis of SNVs, indels and CNVs*.
- Results in Genome One Reports
*CNVs whenever the experimental design permits.