Spatial Transcriptomics
We offer the analysis of transcriptional activity in tissue sections.
Study of gene expression in histological sections.
The Spatial Analysis Workflow, Step by Step
The Spatial Transcriptomics technique measures gene expression without losing track of its location in the tissue, linking cellular structure and activity.
Sequencing and mapping quality control.
Alignment of reads against the reference genome.
Quantification of gene expression at the single cell level.
Reduction of data dimensionality.
Clustering or division of cells into different groups and subgroups.
Analysis of differential gene expression, both global and spatial.
Study of the pattern of cellular evolution or maturation (global and spatial trajectories).
Study of cellular communication patterns (Cell Chat).
Enrichment study, gene ontologies and pathways.
Bioinformatics Services
RESULTS IN GENOME ONE REPORTS
Interactive charts, ready to publish
The results of all analyses result in interactive graphs that can be explored on our Genome One Reports platform and downloaded as PDFs for use in scientific publications.
AVAILABLE ANALYSES
A comprehensive suite of analytics
We offer a complete package of analyses delivered through our web-based Genome One Reports platform.
Expanded package
Complete- Cell Clustering (2D and 3D)
- Spatial clustering
- Differentially expressed genes
- TOP differentially expressed genes
- TOP differentially expressed genes (spatial)
- Path analysis
- Spatial Trajectory Analysis
- Top 10 Genes Expressed (Up and Down) in a Trajectory Line
- Contacts and Intercellular Communication (CellChat)
- Route Enrichment (GSEA and GO Terms)
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THEY TRUST US
Centers and Institutions
Hospitals, universities, and research institutes in Europe and Latin America.
Shall we talk about your spatial project?
We'll help you design your experiment and interpret gene expression in its spatial context. Let us know what you need